I was going to change the [ECM] 33010 - Throttle Max Rotation % vs. RPM: & [ECM] 33012 - Throttle Max Rotation % vs. Pedal: Tables to try and get little better economy on a 2004 5.3 Silverado, I noticed the following 2 warnings from HP Tuners

[ECM] 33010 - Throttle Max Rotation % vs. RPM: Max throttle rotation in relation to RPM. WARNING!!! Modify this table at OWN RISK. Incompatibility of this calibration with the vehicle TAC module calibration may render PCM permanently inoperable.
[ECM] 33012 - Throttle Max Rotation % vs. Pedal: Max throttle rotation in relation to pedal. WARNING!!! Modify this table at OWN RISK. Incompatibility of this calibration with the vehicle TAC module calibration may render PCM permanently inoperable.

My Question is, I thought the max rotation allowed was safe to edit, and the relative position curve was the dangerous one that might not jive with the TAC?
How dangerous is it to edit these two tables?