BOTH need to be done. Injector bank assignment and diagnostic firing order need to be changed in the tune and both the injectors and coils need to be re-pinned at the PCM. Easy way to correct those is copy in the table values from a 5.7 Express van tune. I am running my 5.7 on a modified 6.0L tune in a 1 meg PCM (Green/Blue connectors).
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